Journal of Clinical Review & Case Reports(JCRC)

Department of Medicine, Division of Nephrology and Hypertension, The Mehandru Center for Innovation in Nephrology, Jersey Shore University Medical Center, Hackensack Meridian School of Medicine, Neptune, New Jersey, USA

Publications

• Case Report   
  Renal Salt Wasting: Earliest Manifestation of Rhabdomyolysis, Supreet/Mehand-ru Syndrome
  Author(s): Supreet Kaur, Avais Masud, Prit Paul Singh, Kyrillos Rezkalla, Ranyelenu Efobi, Arif Asif, Tushar Vachharajani and Sushil K. Mehandru*
  
  Acute kidney injury is a feared and common complication of rhabdomyolysis, occurring in 10-40% of hospitalized patients with mortality rate as high as 59% in critically ill patients. However, there is a lack of information in the literature on renal salt wasting in rhabdomyolysis. We report 3 cases of rhabdomyolysis who developed renal salt wasting in presence of normal glomerular filtration rate. To the best of our knowledge, this is the first case report in humans displaying this phenomenon. Authors noted that all the three patients had urine pH of over 7.0. Literature reveals, patients with rhabdomyolysis and urine pH<6.5 develop acute kidney injury whereas urine pH>7.0 experienced renal salt wasting in presence of normal glomerular filtration rate. All 3 cases, previously not known to have hypertension, were noted to have elevated blood pressure during acute phase of rhabdom.. Read More»
  

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