Journal of Clinical Review & Case Reports(JCRC)
ISSN: 2573-9565 | DOI: 10.33140/JCRC
Impact Factor: 1.823
Daniela Degeratu
“Dr Ioan Cantacuzino” Laboratory of Pathology, Bucharest, Romania
Publications
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Case Report
Sister Mary Joseph Nodule, Umbilical Sentinel for an Endometrioid Endometrial Carcinoma in Postmenopause-Challenges for a Multidisciplinary Approach
Author(s): Manuela Cristina Russu*, Adriana Elena Ghelmene, Gabriela Predescu, Daniela Degeratu and Nastasia S
A 82 years old, hypertensive, obese, 1 delivery, menopause at 47 yrs, non-smoker, with history of vaginal bleeding in January 2018, is sent by the dermatologist for an irregular umbilical tumor of 2/1 cm, recurrent at 6 weeks post-ablation, microscopically considered as a carcinomatous metastasis. Abdomino-pelvic MRI rises the suspicion of uterine carcinoma, which is confirmed by endometrial biopsy. It is done extrafascial total hysterectomy with bilateral salpingo-oophorectomy, and pelvic lymph dissection and ablation, plus ablation of a skin-adipose-conjunctive peri-and subumbilical area of 5/4 cm. There were no peritoneal metastases, or other viscera abnormalities. The optic microscopy shows moderate differentiated endometrioid endometrial carcinoma, with areas of squamous differentiation, invasion in external myometrial half, without peritoneal invasion, with vessels metastatic em.. Read More»