X-ray Microanalysis of Normal Primary Tooth Dentine and Primary Tooth Dentine in Teeth Diagnosed Dentinogenesis Imperfecta Type II
Abstract
Noren JG, Sabel N and Cornell DH
Background: Dentinogenesis Imperfecta (DI) is an inherited single-gene disorder affecting the dentine. The mineral concentration in DI type II dentine has been shown to be significantly lower compared to what was found in normal dentine, however, reports of elemental analyses of the dentine in Dentinogenesis Imperfecta are few.
Aim: The aim of this study was to analyse the elemental composition of dentine in primary teeth from children with DI and from normal sound primary teeth using X-ray microanalysis.
Materials and Methods: X-ray microanalysis of the elements C, O, Na, Mg, P, Cl, K and Ca was performed in the dentine of five normal primary teeth and in seven primary teeth diagnosed DI. The analysis was made in a low magnification in 10 points from the enamel-dentine junction/root surface toward the pulp. The data was also evaluated with an inductive analysis. Results: Lower values for C were found in DI-dentine compared with normal dentine. Na had significantly higher values in DI-dentine while Mg had significantly lower values. The inductive analysis revealed that Na and Mg were the most important elements for discriminating DI-dentine from normal dentine.
Conclusion: Dentine in primary teeth from patients diagnosed with Dentinogenesis Imperfecta type II analysed with XRMA have lower values of C and Mg and higher values of O and Na compared with normal primary dentine.