Journal of Pathology and Laboratory Medicine(JPLM)
Utricle With Big C-Follicular T Cell Lymphoma
Abstract
Anubha Bajaji
Follicular T cell lymphoma is an exceptional subtype of nodal lymphoma emerging from T follicular helper (Tfh) cells. The lymphoma demonstrates a nodal, follicular or perifollicular pattern of neoplastic configuration wherein neoplastic cells exhibit an intense, perpetual expression of T follicular helper immune markers. Follicular T cell lymphoma may be associated with Epstein Barr viral infection. Follicular T cell lymphoma manifests clinical and diagnostic features simulating angioimmunoblastic T cell lymphoma(AITL). Appropriate discernment of extra-nodal follicular T cell lymphoma can be challenging, in the absence of categorical follicular T cell lymphoma implicating lymph nodes. Additionally designated as follicular peripheral T cell lymphoma (F-PTCL), follicular T cell lymphoma (FTCL), peripheral T cell lymphoma with nodular, follicular or perifollicular pattern or peripheral T cell lymphoma with follicular involvement, follicular T cell lymphoma manifests ~2% of T cell lymphomas.