Transnasal Neuro-Prolozone for the Management of Trigeminal Neuralgia; Dra-matic and Long-Term Relief of a Novel Technique

Abstract

Zobaida Saleh Al Shiban

We report two cases of trigeminal neuralgia, dramatically relieved with transnasal neuro- prolozone infiltration of the sphenopalatine ganglion. To be mentioned, we are the first to describe this technique in the treatment of trigeminal neuralgia. The two cases had a history of trigeminal neuralgia for more than 2 years, refractory to pharmacological treatment. Case one is a 63 year-old female, with a 5-year history of trigeminal neuralgia. This patient reported a history of hypertension and atrial fibrillation. The second patient, a 33 year-old male, had a 2-year history of trigeminal neuralgia, and a reported history of type-1 diabetes and ischemic heart disease (IHD). No side effects were reported, along the 6-month follow- up period. The Penn Facial Pain Scale Revised (Penn-FPS-R) was conducted to assess pain interference with the quality of life in the included patients, 1-week before injection, 5 minutes, 15 minutes, one week, 4 weeks and 6 months after injection. The patients’ satisfaction and pain intensity were assessed using the 11-point numeric rating scale (NRS) at the pre-defined time points. The two cases reported long-term improvement, regarding pain intensity and quality of life. In conclusion, transnasal neuro-prolozone infiltration is emerging as an effective, long-term and immediate-acting treatment modality for mitigating the burden of trigeminal neuralgia.

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