The Reason for the Size Differences of the Isolated Exosomes and the Importance of these Differences

Abstract

Imren Hasoglu and Ayse Karatug Kacar

Exosomes secrete complex structures surrounded by membrane vesicles out of the cell. These complex structures contain lipids, proteins, and nucleic acids. These secreted structures can also affect other cells. Therefore, exosomes are important for the diagnosis and treatment of various diseases. Exosome sizes can vary. Although this situation is seen in exosomes isolated from different sources, it is also seen in exosomes isolated from the same source. The isolation technique, location of the cell, storage conditions, and storage time are effective. It is important for the accuracy of the data to be obtained and that all isolations are made and applied under the same conditions in the studies.

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