The Effect of Exercise to Glomerular Filtration Barrier System in Diabetic Rat

Abstract

Yensuari, Aywar Zamri, Lindawati, Putu Moda Arsana and Achmad Rudijanto

People with diabetes mellitus are spread all over the world. Currently, it is estimated that nearly 425 million (8.8% of the world population), 20 - 79 years old, most (79%) are in low and middle income countries. The estimated number of people with diabetes will increase in 2045 to 625 million [1]. Along with these results the number of macro and microvascular complications is also expected to increase. About 40% of diabetics experience proteinuria in the form of microalbuminuria which is a sign of the progression of chronic kidney disease. Without special intervention 20-40% of patients with microalbuminuria will develop overtnepropathy and around 20% after 20 years theonsetof overt nepropathy will become CKD (Chronic kidney disease) [2].

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