The Complex Structure of Collagen in the Skin

Abstract

Emanuela-Daniela Grosan and Monica Butnariu

Collagen, ubiquitous component and the most abundant protein in the human body is a biopolymer with an open internal structure, it contains a large number of binding sites available for interaction with various biologically active substances: hormones, enzymes, peptides, etc. Their accessibility to the collagen binding sites is facilitated by its extraordinary hydrophilic capacity. It is also involved, directly or indirectly, in the attachment and differentiation of cells as well as in immunological processes, so that, apart from its structural role, collagen participates in complex processes such as: development, morphogenesis and pathological processes. The variety of collagen types is not, however, the exclusive result of structural differences at the molecular level, it also appears as a result of cellular activity in the process of assembling molecules into supramolecular structures. Thanks to its moisturizing properties, collagen helps prevent and reduce wrinkles, especially the first expression wrinkles. In addition, it contributes to the reduction of pigment spots, improving blood circulation at the same time.

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