The Changes of Electrocardiogram in Neuroleptic Cardiomyopathy

Abstract

Volkov VP

The data of medical records of 81 patients with schizophrenia who died (men – 58, women – 23) were retrospectively studied, almost two thirds of them were aged from 41 to 60 years. Three groups of observations were identified: group me (comparison) – 12 patients receiving antipsychotic therapy, but did not have a cardiac pathology; group II – 44 patients with NCH in the latent stage; group III – 25 patients with manifesting disease (developed and terminal clinical stages). 406 electrocardiograms were analyzed in groups 53, 282 and 71, respectively. Eight most common electrocardiographic signs are considered. Dynamics of certain characteristics was shown to be of value for early diagnostics of neuroleptic cardio toxic side effects.

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