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Superparamagnetic Iron Oxide Nanoparticles in Cancer Theranostics
Abstract
Mohammad Norouzi, Soroosh Derakhshanfar, Mohammad Reza Kazemian and Rodrigo Franca
Superparamagnetic iron oxide nanoparticles (SPIONs) have found extensive applications in both cancer therapy and diagnosis (theranostics) due to their intrinsic magnetic properties. SPIONs can be applied as contrast agents in magnetic resonance imaging while they are considered as efficacious drug carriers for targeted therapeutic systems as well as hyperthermia therapy. In this article, recent advances in application of SPIONs in the realm of cancer theranostics are reviewed. Moreover, biosafety issues arising from SPION application are briefly mentioned.