Spatial Relationship of Metabolomics, Osa and Diabetes Mellitus
Abstract
PV Prabhakar Rao and kandamaran Krishnamurthy
Metabolomics is the study of metabolites, targeted or untargeted. They can be analyzed from body fluids like urine, blood, saliva. They are of low molecular weight (<1KD). These reflect the process involved in the metabolism. The targeted one is restricted to the known metabolites. The untargeted identifies unknown metabolites, known as Metabolomes. Sleep is triphasic consisting of Sleep Latency, synchronized sleep phase (SWS) and Rapid eye moment (REM) phase. This is essentially marshaled by neuro hormonal and metabolic changes.. Several disorders of sleep and associated hormonal imbalances can result in obesity and Diabetes Mellitus. Thus the abnormal metabolimic facsimile can reflect of this patho physiological process. The study of metabolites may pay an inexpensive way to diagnose this problem in future, fortifying or replacing Polysomnography.