Some Notes about Medical Applications for Microbial Biosurfuctants

Abstract

Samer M. Al-Hulu

Biosurfactants are amphiphilic biological compounds generatedby yeast, bacteria and filamentous fungi in extracellular or cell membrane part. It’s made up of a hydrophilic moiety, and a hydrophobic moiety. The biosurfactants advantage includes Biodegradability, low toxicity, Biocompatibility and digestivity, availability of raw materials and specificity. The Medial application for Biosurfactant includes, Antimicrobial activity by having toxicity on cell membrane permeability, Anti-cancer activity,the microbial extracellular glycolipidsused as reagent for cancer cell treatment, Antiviral activity C. bombicola Sophorolipids surfactants is powerful spermicidal and virucidal agent, Anti-adhesive agents, The Adhesion inhibition for pathogenic microbe to solid surfaces or infection site, Anti-Fungal Activity, The P. Flocculosa Flocculosin having antifungal activity against pathogenic yeast and human mycose. Immunological adjuvant, the mixing of Bacterial lipopeptides with classic antigens having active nontoxic, non pyrogenic, Gene delivery, the liposomes based on biosurfactants having higher efficiency for gene trimansfection

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