Screening for Bioactive Compounds in Extracts from Leaves, Leafstalks, and Fruits of Ficus Carica

Abstract

Fatimh Mustafa Meelad and Salem Mohamed Edrah

Aqueous, Ethanol extracts and Fig's milk were preliminary phytochemically screened and tested against some pathogenic bacteria. Qualitatively analysis revealed Tannin, Saponin, Flavonoids and Terpenoids and phlobatannins and Steroids gave positive results. Quantitative analysis showed that the highest percentage of alkaloid was 41% in fig milk and 39% in plant leaves. In addition, the crude extracts of fig's milk as well as of the raw plant extracts were tested (using the Disc Diffusion Method) for their antimicrobial activity against the bacterial pathogens. The influences of aqueous and ethanol extracts on some pathogenic: two strains of gram-positive bacteria include Staphylococcus aureus and Streptococcus pneumonia.., and two strains of gram-negative bacteria including Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, Proteus vulgaris, Salmonella SPP and Klebsiella aerogenes. , and the sensitivity of the microorganisms to the extracts of plant’s species were compared with each other and with designated antibiotics by measuring the diameter of the inhibition zones, After incubation, the zone of inhibition was measured in mm, a good inhibition of more than 6 mm were observed indicating the effective antibacterial activity of the bioactive compounds in both of the plants leaves extracts and fig's milk. Moreover, the including results of the antibacterial activities of plants leaves extracts and fig's milk were discussed regarding their phytochemical components which exhibited that have a good inhibition zone against six tested bacterial strains.

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