Retinopathy of Prematurity and Bioinformatics Analysis: Bibliometric Studies and Visual Analysis by Cite Space

Abstract

Fu Zheng, Yang Hui, Wei Xixiang, Xiong Weiwei, Yin Xue, Fang Weifang and Li Xiuting

Objective: The study aims to explore the hotspots and frontiers of retinopathy of prematurity (ROP) and bioinformatics analysis by reviewing the current status by Cite Space.

Methods: The Web of Science database (WoS) was searched from ROP to 2010. Cite Space is used to generate network maps about the collaboration between authors, countries and institutions and to reveal hotspots and frontiers of both.

Results: 98 studies related to ROP and various bioinformatics analyses were retrieved from WoS. North-Eastern University and Massachusetts General Hospital are the major countries and institutions. Hot topics focus on the interaction between the two, and possible new diagnostic and control measures.

Conclusion: based on the results of the Cite Space study, scholars suggest that the deepening of the authors, positive cooperation between countries and institutions, mainly committed to research including artificial intelligence deep learning and the mutual recognition of biological information, especially through vascularization, additional lesions, classification and gene expression, this may mean that the future may be rapid and accurate diagnosis of ROP, especially invasive retinopathy of premature maturity (A-ROP).

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