Protein-Losing Enteropathy, Anasarca and Dermatological Manifestations on People of Advanced Age: Don't Overlook the Diagnostic Hypothesis of a Cronkhite Canada Syndrome

Abstract

Daniela Tirotta, Roberto Ciserchia, Calogero Amella, Sofia Bersani, Vittorio Durante

Cronkhite-Canada syndrome is a rare and non-genetic syndrome of unknown etiology, characterized by diffuse gastrointestinal polyposis, the dermatological triad (nail distrophy, hyperpigmentation, alopecia), diarrhea, weight loss and abdominal pain.

Herein, we describe a late-onset case that experienced relief after prednisone treatment. It is very important keep in mind the clinical hypothesis of this syndrome, because an early diagnosis can help reduce morbidity and mortality associated with this pathology, which is often life threatening.

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