Practices of Gastroenterologists in Cameroon on the Management of Helicobacter Pylori Infection

Abstract

Tangie Ngek Larry, Ndjitoyap Ndam Antonin Wilson, Kowo Mathurin, Ankouane Andoulo and Njoya Oudou

Background: In Africa and Cameroon in particular, there is no consensus guideline for diagnosis and treatment of Helicobacter pylori infection (HPI). The aim of this study was to describe the current practices on management of H. pylori infection among gastroenterologists in Cameroon and compare with existing guidelines.

Methods: This was an observational and descriptive study from October 1st 2020- July 31st 2021. All consenting gastroenterologist practicing in Cameroon were consecutively included. Data collected included socio-demographic and clinical data (pre-eradication diagnostic tests, treatment schemes and drug regimens, post-eradication control test). Data obtained was analyzed using IBM-SPSS version 26.0.

Results: Fifty participants were approached among which 40 responded giving a response rate of 80%. The mean age of participants was 47.8 ±10.8 years with a male predominance with a sex ratio of 1.85. The median number of years of practice as a gastroenterologist was 9 years (IQR 5.0-18.8). The main pre-eradication diagnostic tests were histology (82.5 %). The main treatment protocols used as first line for eradication were: non-bismuth concomitant quadruple therapy for 28 participants (70.0%). Thirteen participants (32.5%) routinely requested for eradication control. The main post-eradication control test used included: urea breathe test; 22 participants (55.0%), histology; 13 participants (32.5%).

Conclusion: In Cameroon most gastroenterologists had practices like those recommended in the developed world on the management of HPI with some degree of variability. This variability in practices observed highlights the need for local guidelines based on empirical evidence of treatment efficacy, available diagnostic test, and cost- efficiency.

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