Potentiality of Postponing Menopause through Ovarian Auto-graft Transplantation

Abstract

Abdelmonem Awad Hegazy

Menopause is a critical stage in the life of women in which the menses stop with loss of fertility. Deprivation of female hormones especially estrogen might be accompanied with some physical and psychological disorders. Therefore, this mini-review aimed to highlight the anatomy of the ovary at different age stages and to discuss the possibility of using technology of cryopreservation in postponing the menopause to alleviate its associated disorders and ensure healthy life for women. Ovarian tissue cryopreservation has been successfully used for rescuing the harvested ovary from destruction that could be caused by chem- or radiotherapy used in cases of cancer management. Then, slices of such tissues re-implanted into the patients give good results restoring the fertility and hormonal production. Therefore, it is suggested that trials to re-transplant ovarian auto-graft might be performed to postpone the menopause in volunteers in order to preserve endocrine function of ovary.

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