Phytochemical Investigation on The Root Extract of Teclea Nobilis

Abstract

Tewodroes Mulu, Legesse Adane, Dessalegne Bekele, Fillipo Tamru, Tizazu Sorsa

Teclea nobilis is one of an endemic species to Ethiopia. It is used as a traditional medicine to treat analgesics and other disorders. Although many species of the genus Teclea have been investigated for their chemical constituents, there is no much prior report on the investigation of chemical constituents of root of Teclea nobilis. Phytochemical screening of the C6 H14, CH2 Cl2 ,CH2 Cl2 /CH3 OH (1:1) and CH3 OH root extracts of the plant revealed the presence of alkaloids, flavonoids, terpenes, phenols, tannins and glycosides.Chromatographic separation using column chromatography of CH2 Cl2 /CH3 OH (1:1) result in isolation of three compounds namely compound TN1(0.06%), TN2(0.04%)and TN3(0.05%).Structure are proposed for Compound TN1 and compound TN2 .Compound TN3 was not fully characterized due to lack of adequate spectral data.

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