Papillary Thyroid Carcinoma Synchronous with High-Grade Non-Hodgkin's Lymphoma: A Case Report
Abstract
Zakaria El Hafi, Khalil Hjaouj, Razika Bencheikh, Mohamed Anass Benbouzid, Adelilah Oujilal and Leila Essakalli
Papillary thyroid carcinoma (PTC) is the most common thyroid carcinoma, accounting for up to 90% of all thyroid malignancies. The association with a hematological malignancy is very rare, representing an incidence of only 7%. We present a case of synchronous papillary thyroid cancer and non-Hodgkin's lymphoma (NHL) and discuss possible dilemmas in diagnosis and treatment. A 60-year-old woman with no medical or radiation history presented with a hard, immobile left supraclavicular swelling. Cervical ultrasound showed the presence of a suspicious-looking supraclavicular adenopathy with two right lobar thyroid nodules classified EU-TIRADS 4. We performed a total thyroidectomy with right central latero-cervical functional left curage and excision of the left supraclavicular adenopathy. Pathological examination revealed papillary thyroid carcinoma synchronous with high-grade non- Hodgkin's lymphoma. After a multidisciplinary consultation, the patient received six courses of chemotherapy before undergoing irratherapy. This article highlights the importance of a multidisciplinary approach in the absence of consensus, given the rarity of this case.