Olea Europaea Leaves Delay the Onset of Toxicity of Cerastes Cerastes Venom in Albino Mice

Abstract

Enas A. Sadawe, Alla M. Hashkel, Halima A. Gbaj, Asia Mohamed, Nesren M. Magel, Salah M. Bensaber, Fathi M Sherif , Massaud S. Maamar, Anton Hermann and Abdul M. Gbaj

To investigate the anti-Cerastes cerastes venom effect of aqueous olive leaf extract. The mitigation in the mean survival time of the male Albino Swiss mice were used to deduce the antivenom property of the aqueous olive leaf extract after challenging with LD99 of snake venom. The aqueous extract of olive leaf significantly increases mean survival time and the protection fold, but could not protect mice from death when used alone. The higher dose, i.e., 33 g/kg was better than that of the lower dose of 15 g/kg. The anti-snake venom was found to be more effective than the aqueous olive leaf extract.

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