Journal of Pharmaceutical Research(JPR)
ISSN: 2573-962X | DOI: 10.33140/JPR
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Nephroprotective Effect of Hydroalcoholic Extract of Manikara Zapota on Cisplatin Induced Nephrotoxicity in Male Wistar Rats
Abstract
B Maheshwari Reddy, CH. B. Praveena Devi and S K Sushma Taj
Nephrotoxicity is known to be a major complication during cisplatin chemotherapy in cancer patients. Cisplatin is a highly effective chemotherapeutic agent; its clinical use is severely limited by serious side effects as nephrotoxicity. The aim of this study is to evaluate the nephroprotective activity of hydroalcoholic extract of Manikara zapota (MZ) against cisplatin (CP)- induced renal damage using albino rats.