Investigation of Close Relationship Between Cancers and Diabetes Based on an UK Study and One T2d Patient’s Collected Data Using the Viscoplastic Energy Model of GH-Method: Math-Physical Medicine (No. 1034, Viscoelastic Medicine Theory #432)

Abstract

Gerald C. Hsu

The author recently reviewed a published report from the NIH and Lancet titled "Trends in Predominant Causes of Death in Individuals with and without Diabetes in England from 2001 to 2018: An Epidemiological Analysis of Linked Primary Care Records" by Jonathan Pearson-Stuttard et al., published in Lancet Diabetes Endocrinol in 2021 (volume 9, issue 3, pages 165- 173). This study, referred to here as the “UK study”, examined various medical complications versus diabetes but the author of this paper decided to specifically focus on cancers.

The NIH/Lancet study found that out of every 1,000 individuals, there are 7.7 (range 7.4-8.0) with diabetes and 4.4 (range 4.3- 4.6) without diabetes, leading to the UK Study’s cancer ratio of 1.75 between those with diabetes and those without diabetes.

Utilizing a self-developed mathematical model called the Metabolic Index (MI) Model, the author calculated his annual cancer risk percentage based on 10 selected influential categories and 500 defined input elements. The MI model calculated cancer risk ratio between the first two years (2010 and 2011, marked by severe diabetes with an average A1C of 10.25%) and the most recent two years (2023 and 2024, with well-controlled A1C at 6.1%) was 1.74 (62.5% earlier cancer risk divided by 36.0% recent cancer risk).

Further, applying the Space-Domain Viscoplastic Energy Model (SD-VMT), the author estimated the energy generated through the interaction between cancer risk percentage (output strain) and three influential stresses (FPG indicating pancreatic beta cells health state, HbA1C indicating the severity of Type 2 Diabetes, and body weight indicating the primary cause of many metabolic disorders, including both T2D and cancers). The SD-VMT model showed a cancer energy ratio of 1.88 between the initial two years (2010 and 2011 with severe diabetes) and the most recent two years (2023 and 2024 with controlled diabetes), calculated as earlier energy of 56 divided by recent energy of 30.

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