Incidence of Hepatitis E Virus Among Elevated Liver Enzyme (Alt, Ast) Sudanese Patients, Khartoum, Sudan

Abstract

Myada Ahmed Musa Haroon, Amira Altom Fawzi Osman

Background: Hepatitis E Virus (HEV) infection is a newly recognized serious threat to global public health and Africa is suspected to be among the most severely affected regions in the world.

Objective: This study aimed to detect the frequency of anti-hepatitis E IgM, among elevated liver enzyme patients.

Methods: The current study is descriptive cross-sectional study carried out between April to august 2016, Ninety Patients with high liver enzyme ALT&AST and non B non C hepatitis attended Ibn senaa hospital Khartoum north, Omdurman teaching hospital and bahri teaching hospital bahri north, sedan were collected and tested by using (ELISA).

Results: It show that Out of the 90 samples tested in order to evaluate the effect of age on HEV seropositivity, there was a significant difference (P< 0.05) between HEV seropositivity and age group.

Conclusion: study demonstrates the high prevalence rate of HEV seropositivity among non-hepatitis patients with high level enzyme ALT, AST. This will raise the potential risk of HEV infection by blood transfusion and may be the source of the outbreak.

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