Impact of a Glycosaminoglycan and Type II Collagen Supplement (Glycosane®) On Mobility and Quality of Life in Senior Dogs: A Pet-Owner Evaluation

Abstract

Navarro C, Delaup V, Lacreusette M, Jahier B, Destaing C and Gard C

As dogs age, the decline in mobility is a common physiological change. The incorporation of complementary feeds can be an effective strategy to support and preserve joint function and mobility, contributing to the maintenance of overall musculoskeletal health and comfort in geriatric dogs. Privately owned dogs aged over six years, exhibiting reduced mobility and no changes in their mobility management within the last three months, were recruited for this study. They were administered a chicken cartilage hydrolysate complementary feed containing a complex of glycosaminoglycans and type II collagen (Glycosane®, MP Labo, France) once daily for 56 days. Assessments were conducted at baseline (D0) and follow-up visits at D7, D28, and D56. Mobility, pain intensity, and pain interference were evaluated using a revised Liverpool Osteoarthritis in Dogs (LOAD) scale and a Canine Brief Pain Inventory (CBPI). Owners also completed a questionnaire assessing quality of life (QoL), with seven questions on the animal’s well-being (QoL1) and seven questions on the owner’s well-being (QoL2). A total of 21 dogs were included in the study, with 71% of owners reporting enhanced mobility by D56. Notable improvements were observed in half of the cases after 21 days of supplementation, with 39% of cases showing significant changes as early as 14 days. Revised LOAD scores demonstrated a significant improvement over time (p=0.0019). CBPI severity scores decreased significantly from baseline to D28 and D56 (p=0.0300 and p=0.0271, respectively). The CBPI QoL score also significantly improved at D56 compared to D7 (p=0.0440). The overall QoL score showed a significant improvement by D56 compared to baseline (p=0.0089), with a particular improvement in QoL1 (p=0.0015). The supplement was rated highly for ease of use (mean score 4.4/5), with an excellent compliance (95%). This complementary feed demonstrates significant benefits in enhancing mobility and quality of life in senior dogs. Its high ease of administration supports owner compliance and satisfaction. These findings suggest that Glycosane® is a valuable nutritional aid in maintaining canine mobility. Further studies with larger cohorts and a controlled group are recommended to confirm these results.

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