Guillain-barre syndrome and sars-cov2 corona virus. Vaccinate or get infected with covid? What poses less risk?

Abstract

Maria Dolores Calabria Gallego

Introduction: Among the neurological diseases possibly associated with COVID-19 (coronavirus disease 2019) infection, Guillain-Barré syndrome has been postulated since the start of the pandemic, even more so when vaccination has also come into play. Objectives: A bibliographic review is carried out to assess the true risks of suffering Guillain-Barré syndrome secondary to vaccination against SARS-COV2 (severe acute respiratory syndrome coronavirus 2) infection and of developing it secondary to SARS-COV2 infection. Material and Methods: A search for articles was carried out in the PubMed-MEDLINE database between June 2021 and July 2021. Results: The scarcity of studies that can provide solid evidence stands out, with most of the publications being clinical case reports or case series. Two epidemiological studies with contradictory results stand out. Conclusion: With the information currently available, it is not possible to conclude that there is an association between SARS-COV2 infection or secondary to vaccination with Guillain-Barré syndrome. Therefore, the recommendation to avoid vaccination for fear of a recurrence of Guillain-Barré syndrome does not seem to be normative at the present time.

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