Fatty Liver, Developing Factors and the Outcomes

Abstract

Behina Babaalizadeh, Maryam Bahmanyar, Mohammad Hassan Meshkibaf and Behnoosh Miladpour

Fatty liver has grown increasingly in recent decades. Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease in the United States with a prevalence of 30% and the leading cause of liver disease with a mortality rate of 25.2% in the world. Fatty liver is divided into two types, alcoholic and non-alcoholic. It has been reported that 44% of NAFLD patients progress to nonalcoholic steatohepatitis (NASH) at the second biopsy, and in several countries, hepatocellular carcinoma is the most common disease. Unfortunately, no absolute cure has yet been found. Finding out about related diseases, genetics, lifestyle, mechanisms, and signaling pathways may have a great impact on discovering the best ways to treat fatty liver. In this study, we tried to present the most important components in developing this disease.

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