Factors Associated with Perinatal Death in Women with Twin Pregnancies at The Kindia Regional Hospital Maternity Ward

Abstract

Diallo Fatoumata Bamba, Kadio Kadio Jean-Jacques Olivier, Bah Oumou Hawa, Sow Alhassane II, Grovogui Fassou Mathias, Diallo Fatoumata Binta Sigon, Toure Abdoulaye, Balde Ibrahima Sory and Sy Telly

Introduction: Twin pregnancies are high-risk pregnancies, especially for the second twin, with very high perinatal mortality. The aim of this study was to identify factors associated with perinatal death in newborns in a level II hospital in Guinea.

Methods: This was a cross-sectional study lasting twelve (12) months, from September 01, 2022 to August 31, 2023, carried out in the maternity ward of Kindia regional hospital. Multivariate regression analysis was performed to investigate factors independently associated with death in the first and second twins. A value of P<0.05 was considered significant.

Results: Perinatal death was higher in the second twin (27.7%) than in the first twin (17.3%). Factors associated with perinatal death in the first twin were prematurity (ORa=3.18, 95%-IC= 1.30-7.88), pre-eclampsia (ORa=3.30, 95%- IC=1.11-9.53) and hydramnios (ORa=6.43, 95%-IC=1.21-37. 5) and in the second twin, prematurity (ORa=2.31, 95%- IC=1.00-5.25), ultrasound (ORa=0.38, 95%-IC=0.18-0.81), monozygotic pregnancy (ORa=2.58, 95%-IC=1.03-6.40), and threatened preterm delivery (ORa=4.93, 95%-IC=1.49-17.7).

Conclusion: Factors associated with perinatal death were highly significant in the second twin compared with the first twin, with a strong association with prematurity.

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