Evaluate the Dexamethasone Drug as Preventing Repeated Fever by Acute Tonsillitis in Pediatric Patients: A Prospective Study

Abstract

Ahmed Ali Ebshena and Zubaeda M Alsayeh

Background: To determine the effectiveness of dexamethasone drug in reducing the pain and fever associated with moderate to severe Acute tonsilitis in pediatric patients.

Methods: Prospective, randomized, Ethics approval was to complete all parts of the form and append consent form(s), information sheets, and any other materials in support of consent. The Institutional Review Board of the Faculty of Medical Technology, affiliated with Sabratha University in a Libyan pediatric department (PED) between March to July 2024, Children aged 5 to 12 years with moderate to severe Acute tonsillitis. Study patients were randomly assigned to receive dexamethasone drug (0.6 mg/kg with a maximum of 10 mg). Daily follow-up was conducted until the complete resolution of the sore throat. outcome variables included hours to initial relief of sore throat and time to the complete resolution of pain and fever.

Results: A convenience sample of 57 patients were randomized to receive either dexamethasone. patients available for data analysis; 57 received dexamethasone. Patients who received dexamethasone reported earlier onset of pain and fever relief (9.2 vs 18.2 hours; P,.001), and fewer hours to complete resolution of sore throat (30.3 vs 43.8 hours; P=.04). less time to complete resolution of sore throat (37.9 vs 70.8 hours; P=.006).

Conclusions: Children with moderate to severe acute tonsilitis had an earlier onset of pain and fever relief and a shorter duration of sore throat when given dexamethasone drug.

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