Estimating Cardiovascular Disease Risk and Insulin Resistance via Transforming Glucose Wave Fluctuations from Time Domain into Associated Energy in Frequency Domain and Applying the Linear Elastic Glucose Theory of GH-Method: Math-Physical Medicine, LEGT Part 21 (No. 403)

Abstract

Gerald C Hsu

In this article, the author provides his personal perceptions and opinions regarding the concept and approach of “Glycemic Variability” (GV). Instead of using certain newly defined biomarkers by other research scientists, such as the mean amplitude glycemic excursions (MAGE), he chose to study the glucose wave fluctuations via a simple yet straightforward expression of the magnitude of glucose wave variances. He uses his simple definition of a glucose wave fluctuation equals to the maximum glucose value minus the minimum glucose value. Furthermore, he selected the postprandial plasma glucose (PPG) wave fluctuations from two distinctive periods consisting of 230 days each: the beginning collection of his sensor glucose data of Period A from 5/15/2018 to 12/31/2018 (Y2018) and the most recent Period B from 7/1/2020 to 2/16/2021 (Y2020).

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