Effect of Oral Nigella Sativa on Fasting Blood Glucose in Adults

Abstract

Omer M Khalid, Mohamed Eltayeb, Ibrahim A Ali, Omer A Musa

Introduction: Nigella Sativa is widely used traditional medicinal plant throughout the world as seeds and oil. It has been used to treat a wide range of disorders including Diabetes Mellitus (DM).

Objective: Effect of oral Nigella Sativa on fasting blood glucose in non-diabetic individuals.

Methods: A cross sectional study was conducted on 10 healthy non diabetic volunteers aged 20-35 years with normal fasting blood glucose (FBG). Subjects were given Nigella Sativa seeds orally (4gm) twice per day for 2 days. FBG was measured before and after Nigella Sativa supplementation by glucose oxidase methods using bio system A25.

Results: The level of the fasting blood glucose was 99.4±3.1 mg/dl in the first day and deceased to 93.1±4.6 mg/dl after Nigella Sativa administration, which was statistically significant (p. value= 0.031).

Conclusion: Nigella Sativa significantly reduced the level of blood glucose among non-diabetics adults. The mechanism of action of Nigella sativa needs to be investigated.

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