COVID-19-Related Sarcoidosis

Abstract

Attapon Cheepsattayakorn, Ruangrong Cheepsattayakorn and Porntep Siriwanarangsun

Several post-COVID-19 inflammatory disorders and autoimmune diseases have been discovered [1] since global COVID-19 pandemic started [2]. Association between these diseases is still to be investigated [2]. Common genes between COVID-19 and sarcoidosis are demonstrated in Figure 1, 2 [3]. Nevertheless, sarcoidosis organ involvement, demographics, and type of sarcoidosis treatment at the time of COVID-19 diagnosis are related to hospital admission, non-invasive ventilation or high flow oxygenation, intubation [4]. A retrospective hospital- based cohort study of 585 French sarcoidosis patients in 2017, demonstrated an estimate of a 5 % frequency of severe infections that resulting in hospital admission and death [5]. A typical HRCT feature in sarcoidosis is the presence of well- defined micronodules scattered along the broncho-vascular bundle, veins, fissures and pleura in a characteristic lymphatic distribution. Occasionally, “ galaxy sign ”,a highly suggestive of pulmonary sarcoidosis (predominance of a mid-to-upper lung zones) may demonstrates conglomerate masses that are surrounded by a multitude of micronodules (Figure 3) [6].

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