Commentary on the Challenges of Clinical Trials in Developing Nations: Ethiopian Perspectives

Abstract

Etsubdink Abera Aboye

Clinical trials in Ethiopia and other developing nations can generally be considered to be in its embryonic stages. Despite that, motivation of the researchers and efforts to establish clinical trials unit in academic and research institutions is encouraging. This is reflected by increasing clinical trials registered from Ethiopia in trial registration database. Besides, some of the trials conducted in Ethiopia have informed treatment guidelines. However, trained workforce, governmental support, research infrastructure as well as financial support remain weak. Inter-sectoral collaborations, sustainable financial support, training of academic staff to conduct clinical trials and the commitment and engagement of the leadership in research are all important. There is a need for enhanced socio-economic development and translation of research findings into locally relevant evidence. The objective of this commentary is to reflect on the challenges of Clinical trials in developing nations: Ethiopian perspectives to identify the challenges, and use the opportunity to engage in clinical trials for the better health of the poor people.

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