International Journal of Clinical & Experimental Dermatology(IJCED)
ISSN: 2476-2415 | DOI: 10.33140/IJCED
Impact Factor: 1.9
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Blister as A Cutaneous Manifestation of Sjogren s Syndrome Determines IL 6 Antibody to Be A Potential Treatment: A Case Report
Abstract
Qiannan Xu, and Jie Zheng
A 64 years old female was admitted to hospital due to having repeated blister on skin. Her Dsg1, Dsg3, Bp180, Bp230, VII collagen antibodies were all negative while her ENA-SSA and anti-CCP were positive. Labial glands biopsy revealed that lymphocytes immersed around the glands and a diagnose of Sjögren’s syndrome (SS) was made. Skin biopsy indicated subcorneal pustular with neutrophils immersed and direct immune fluorescence as well as blood and blister fluid culture were negative.