Bibliometric Analysis of Breast Cancer and Circular RNA Research Trends from 2002 to 2022

Abstract

Sixia Zhong, Xiuli Zhang, Yun Li, Meili Zhang and Huannan Cao

A bibliometric analysis aims to evaluate the research hotspots and emerging trends in breast cancer and circular RNA, offering new perspectives for researchers in future studies.Methods: This study utilizes bibliometric analysis software, such as VOSviewer and CiteSpace, to analyze literature on breast cancer and circular RNAs from 2002 to 2022, assessing bibliometric characteristics. Specifically, it includes a comprehensive evaluation of publication volume, country/region distribution, institutional sources, publishing journals, citation frequency, H-index, and research hotspots.Results:Through screening the Web of Science database, a total of 787 relevant publications were identified. Over time, the number of articles has shown a growing trend. In the field of breast cancer and circular RNA research, China holds a dominant position, with research institutions in the United States and Iran also being significant contributors. Fang Lin is the most prolific author, followed by Yang Burton B., Tang Hailin, Wang Xuehui, and Xie Xiaoming. "Frontiers in Oncology" and "Molecular Cancer" are the journals with the highest number of publications. The proliferation and migration of tumor cells remain hot research topics. Keywords have gradually shifted from "cell growth," "messenger RNAs," and "biomarker" to "long noncoding RNAs" and "sponge," indicating continuous updates and developments in this field. "Long noncoding RNAs" and "sponge" are likely to become future research hotspots.Conclusion: Bibliometric analysis provides valuable information for research on breast cancer and circular RNAs. In recent years, studies related to the mechanisms of breast cancer and the biological functions of circular RNAs have gained significant attention.

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