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Articular Cartilage: The Destruction of Bilayers and Deactivation of Phospholipid Molecules
Abstract
Zenon Pawlak, Aleksandra Mre
To our knowleadge the coaugulation by interacton of β2 -Glycoprotein I (β2 -GP I) with the phospholipid membrane is required to verify this hypothesis. The open hockey stick-like conformation occurs when protonated amino acid functional group (-NH3 +) β2-GP I is complexed to negatively charged phospholipids functional group (-PO4 - ) resulting in the destruction of bilayers and the deactivation of phospholipid molecules.