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Approach to Incident Reduction of Postoperative Nausea and Vomiting (PONV) Following Office-Based Surgery
Abstract
Rose Berkun, Benjamin Khechen and Ryan Berkun
Modern PONV risk research began in the 1990s with publication of studies using logistic regression analysis to simultaneously identify multiple independent PONV predictors and publication of meta-analyses and systematic reviews. This literature shows that female gender post-puberty, nonsmoking status, history of PONV or motion sickness, childhood after infancy and younger adulthood, increasing duration of surgery, use of volatile anesthetics, nitrous oxide, large-dose neostigmine and intraoperative or postoperative opioids are well established PONV risk factors