Allergy Evaluation under X-Ray Exposition in Patients with Failed or Upcoming Arthroplasty

Abstract

Diana Hristova, Petko Genov , Vladimir Stefanov

Nowadays metal implants are a major source of metal exposure. Contact allergy to nickel, cobalt and chromium is one of the most prevalent allergic reactions in humans with contact dermatitis; up to 17% of women and 3% of men. Setting up the sensitization to implant components is needed before orthopedic surgeon. Patch testing remains the gold standard for verification a for type IV reaction of metal, bone cement, or antibiotic. We assessed the records of all 22 patients, whom we followed up since orthopedic intervention or were indicated for such intervention. All patients were exposed to X-ray after placement of epicutaneous tests. X-ray exposure may have influence on positive skin test results- odds ratio 0.56 [95% confidence interval 0.16393 - 1.91031]

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