A Review On: Herbal, Pharmacognostical and Pharmacological Studies on Guggulu

Abstract

Radheshyam, Jainul Basher, Ruchi Singh, Prabha Shankar Maurya, Rajib Singh

Guggulu is an oleogum resin (oleo resin) that spontaneously emerges from the bark of Commiphora mukul Hook. ex Stocks, which belongs to the Burseraceae family. It has a long ethnomedicinal history and is a phytochemical repository of heuristic medical qualities. Guggulu is one of the constituents in several Ayurvedic formulations, the majority of which are titled with the suffix ‘guggulu.’ Guggulsterone is the principal active ingredient in gugulipid, a C. mukul extract used to treat a range of human illnesses. Massive work was expended in this review to assemble the data about guggulu and its undiscovered Ayurvedic formulations utilised in the Ayurvedic System of Medicines. Purified guggulu has been found to be useful in a variety of guggulu formulations for a variety of illness problems, with or without particular anupana. In Ayurveda, the formulation concept of guggulu is characterized by improved pharmacokinetic and polyvalent effects with multiple mechanisms of drug action. As a result, it is necessary in the modern period to undertake preclinical and clinical trials to validate the medicinal effectiveness of Guggulu formulations referenced in ancient literatures.

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