A Rare Case of Kasabach-Merritt Syndrome Presenting with Infantile Hemangioma

Abstract

Sumeyye Uzkan, Gokalp Rustem Aksoy and Yunus Murat Akcabelen

Infantile hemangioma is a proliferative hamartoma of the vascular endothelium, with factors such as GLUT-1 receptors, increased vascular growth factors, and inappropriate distribution of chorionic villus cells during fetal life playing a role in its etiology and pathogenesis [1]. The association of hemangioma with thrombocytopenia and hypofibrinogenemia was first described in 1940 by Kasabach and Merritt, who reported a baby with a giant capillary hemangioma and thrombocytopenic purpura [1,2]. The classic triad of Kasabach-Merritt Syndrome consists of hemangioma, thrombocytopenia, and hypofibrinogenemia [2]. A case of Kasabach-Merritt Syndrome was presented, which was identified on antenatal ultrasound as a liver hemangioma and followed up during the postnatal period.

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