A Journey of COVID 19 from Pathogenesis to Therapy

Abstract

Rupali Sharma, Reetu Malik, Satish Sardana, Shekhar Sharma and Shabnam Thakur

The novel Corona virus has come up from China, the first outburst of this Pandemic disease was reported in Wuhan, China in December 2019. Hence it is named as Covid-19. The other forms such as SARS and MERS have already prevailed in the nature, but this Covid-19 is more lethal than the those. In this review the author wants to focus on the epidemiology, pathogenesis & Current treatment scenario with little impact on Ayurveda used during this outbreak. The novel Corona virus is very contagious disease which propagates rapidly via droplets of saliva and other bodily fluids. Currently, confirmation of 2019-nCoV infection is performed at CDC using the CDC real-time RT-PCR assay for 2019-nCoV on respiratory specimens (which can include nasopharyngeal or oropharyngeal aspirates or washes, nasopharyngeal or oropharyngeal swabs, bronchioalveolar lavage, tracheal aspirates, or sputum) and serum. There are some new developing approaches, for example artificial learning (AI), and high throughput screenings can possibly accelerate the revelation of treatment. During this Outburst of Corona Virus, it is necessary & need of time to form collaborations across the world to debacle this outbreak. The Researchers now re-emphasized importance in evolving the broad-spectrum Antiviral Drugs to battle the effects of this COVID-19 Virus. There are many antiViral drugs and vaccines which are under clinical trials. The rapid spread of disease permits intense surveillance and isolation protocols to prevent further transmission.

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