A Comparative Evaluation: Dexmedetomidine vs. Magnesium Sulfate for Hemodynamic Stability in Laparoscopic Cholecystectomy
Abstract
Dr. Kusum Bilwal, Dr. Sheetal M Shah, Dr. Saumil Shah, Dr. Nihal Umath, Dr. Ramde Bera and Dr. Vismit Gami
Laparoscopic cholecystectomy, a minimally invasive procedure, poses significant anesthetic challenges due to hemodynamic fluctuations caused by pneumoperitoneum and endotracheal intubation. This study compares the efficacy of intravenous dexmedetomidine and magnesium sulfate in stabilizing hemodynamic parameters during anesthesia. A randomized controlled trial was conducted on 60 ASA I-II patients undergoing laparoscopic cholecystectomy. Parameters such as heart rate, blood pressure, sedation, and analgesia were assessed. Results indicate that both drugs effectively attenuate hemodynamic responses, with magnesium sulfate offering superior stability. Dexmedetomidine provided better postoperative sedation. Both agents are valuable anesthetic adjuncts, enhancing patient safety and recovery.