A Brief Overview of Nanozyme-Based Colorimetric and Fluorometric Sensors for Early Diagnosis of COVID-19

Abstract

Saeed Reza Hormozi Jangi

Currently, there are several methods for diagnosis of COVID-19 such as real-time reverse transcription-polymerase chain reaction, hematology examination, polymerase chain reaction, diagnostic guidelines based on clinical features, Chest CT scans, etc. However, yet actual testing methods to identify SARS-CoV-2 are limited. Besides, diagnosis of this new pandemic over SARS, MERS, and H1N1 is one of the most challenges of this field due to their very similar clinical characteristics. To overcome these difficulties, recently, nanozmyes-based systems have been applied for fast, accurate, reliable, and cost-effective early diagnosis of COVID-19. The aim of this review is quick overview of the nanozyme-based sensing and detection colorimetric and fluorometric methods toward early diagnosis of COVID-19. In this regard, the historical background of COVID-19 and its current diagnostic methods were reviewed. Afterward, the nanozymes were introduced and their biomedical applications were discussed. Finally, the recent progress of early diagnosis of COVID-19 based on nanozymatic systems was reviewed.

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