During whole genome sequencing, researchers collect a DNA sample and then determine the identity of the 3 billion nucleotides that compose the human genome. The very first human genome was completed in 2003 as part of the Human Genome Project, which was formally started in 1990. Today, sequencing technology is much more efficient, and a human genome can be sequenced in a matter of days for under $10,000. The first human genome cost $2.7 billion. Today, most genetic testing focuses on one or a few genes, rather than the entire genome. However, with the falling cost of genome sequencing, more individuals are pursuing this option. Physicians can look at an entire genome to see how specific treatments for a disease will be affected by an individual’s unique genetics. For example, the physician may opt to look at genes involved in drug metabolism when deciding dosage. In the future, whole genome sequencing may enable everyone to develop a personalized treatment plan. Creating personalized plans to treat disease may be possible based not only on the mutant genes causing a disease, but also other genes in the patient’s genome. Genotyping cancer cells and understanding what genes are mis-regulated allows physicians to select the best chemotherapy and potentially expose the patient to less toxic treatment since the therapy is tailored.  Previously unknown genes may be identified as contributing to a disease state. Traditional genetic testing looks only at the common “troublemaker” genes. Lifestyle or environmental changes that can mediate the effects of genetic predisposition may be identified and then moderated. Whole genome sequencing is apparently the way toward deciding the total DNA succession of a life form's genome at a solitary time. whole-genome sequencing high impact factor journals has been successfully publishing quality research articles from many years and looking forward to frame up an eminent, outstanding issue with best quality research articles in this year. We request you to kindly submit and publish your paper in the best journal and get global acknowledgement