Vitiligo is a disease that causes the loss of skin color in blotches. The extent and rate of color loss from vitiligo is capricious. It affect the skin on any component of your body, hair, inside of the mouth and even the ocular perceivers.Vitiligo occurs when the cells that engender melanin die or stop functioning. Vitiligo affects people of all skin types. The main designation of vitiligo is color (pigment) loss that engenders light or white patches on your skin. Conventionally, the discoloration first shows on sun-exposed areas, such as the hands, feet, arms, face and lips. Vitiligo signs include skin discoloration, premature whitening or graying of the hair on your scalp, ocular lashes, eyebrows or beard, loss of color in the tissues that line the inside of your mouth and nasal discerner, loss of or transmutation in color of the inner layer of the retina, discolored patches around the armpits, navel, genitals and rectum. Depending on the type of vitiligo, the discolored patches may cover in many components of your body, only one side or part of your body and one or only a few areas of your body. Vitiligo may be caused due to Family history, disorder in which your immune system attacks and eradicates the melanocytes in the skin or a trigger event, such as sunburn, stress or exposure to industrial chemicals Open access to the scientific literature designates the abstraction of barriers (including price barriers) from accessing scholarly work. There are two parallel; towards open access: Open Access articles and self-archiving. Open Access articles are immediately, liberatingly available on their Web site, a model mostly funded by charges paid by the author (customarily through a research grant). The alternative for a researcher is (i.e., to publish in a traditional journal, where only subscribers have immediate access, but to make the article available on their personal and/or institutional Web sites (including soi-disant repositories or archives)), which is a practice sanctioned by many scholarly journals. Open Access raises practical and policy questions for philomaths, publishers, funders, and policymakers homogeneous, including what the return on investment is when paying an article processing fee to publish in an Open Access articles, or whether investments into institutional repositories should be made and whether self-archiving should be made obligatory, as contemplated by some funders. The top online publishing journals publish articles which are cited as references by many authors in their work. Citations are important for a journal to get impact factor. Impact factor is a measure reflecting the average number of citations to recent articles published in the journal. The impact of the journal is influenced by impact factor, the journals with high impact factor are considered more important than those with lower ones. Indexing provides easy access of the article online. The international journals are among the best open access journals in the world, set out to publish the most comprehensive, relevant and reliable information based on the current research and development on a variety of subjects. This information can be published in our peer reviewed journal with impact factors and are calculated using citations not only from research articles but also review articles (which tend to receive more citations), editorials, letters, meeting abstracts, short communications, and case reports. The inclusion of these publications provides the opportunity for editors and publishers to manipulate the ratio used to calculate the impact factor and try to increase their number rapidly. Impact factor plays a major role for the particular journal.