Toxic kinetics is defined as the passage through the body of a toxic agent or its metabolites ,Toxicokinetics is the study of systemic exposure during toxicological experiments. The objective is to quantify the systemic exposure and potentially relate that to toxicology findings. The comparison of toxicology exposure parameters to therapeutically effective exposure parameters gives rise to the idea of a therapeutic window, or the space between efficacy and toxicity. This is depicted in a theoretical example below. The open access journals are peer reviewed scholarly journals of Journals of Environmental Analytical Chemistry. The top open access journals are freely available on the public internet domain, allowing any end users to read, download, copy, distribute, prink, search or link to the full texts of the articles. These provide high quality, meticulously reviewed and rapid publication, to cater the insistent need of scientific community. These journals are indexed with all their citations noted.