The liver is the largest organ in the body. It is located below the diaphragm in the right upper quadrant of the abdominal cavity. An adult's liver weighs approximately 3 pounds and extends approximately from the right 5th rib to the lower border of the rib cage. The liver is separated into a right and left lobe, separated by the falciform ligament. The right lobe is much larger than the left lobe. The working cells of the liver are known as hepatocytes. Hepatocytes have a unique capacity to reproduce in response to liver injury. Liver regeneration can occur after surgical removal of a portion of the liver or after injuries that destroy parts of the liver. Although the liver's ability to react to damage and repair itself is remarkable, repetitive insults can produce liver failure and death. The liver is a metabolically active organ responsible for many vital life functions. The primary functions of the liver are: Bile production and excretion, Excretion of bilirubin, cholesterol, hormones, and drugs, Metabolism of fats, proteins, and carbohydrates, Enzyme activation, Storage of glycogen, vitamins, and minerals, Synthesis of plasma proteins, such as albumin, and clotting factors, Blood detoxification and purification. Due to these important activities, the liver is exposed to a number of insults and is one of the body's organs most subject to injury.