Disease may be prevented or avoided using a number of strategies, including proper sanitation, proper nutrition, frequent exercise and vaccination. Treatments for disease range from medication and medical devices to surgery to self-care. Diseases may be cured simply by time, whereas others require a set of treatments that reverse the disease processes or end the root medical problem permanently. Some diseases may not be cured, in which case the symptoms of the disease may be treated using pain management therapy or palliative care. Humans generally associate disease with pain, distress or social problems. Atypical variations of structure and function, deviant behaviors, disabilities, disorders, injuries, infections and syndromes may be the signs of disease or may be confused with actual disease processes. The information can be published in our peer reviewed journal with impact factors and are calculated using citations not only from research articles but also review articles (which tend to receive more citations), editorials, letters, meeting abstracts, short communications, and case reports. The inclusion of these publications provides the opportunity for editors and publishers to manipulate the ratio used to calculate the impact factor and try to increase their number rapidly. Impact factor plays a major role for the particular journal. Journal with higher impact factor is considered to be more important than other ones.