Thyroid nodules are common entities, frequently discovered in clinical practice, either during physical examination, but also incidentally, during various imaging procedures. They are clinically important primarily due to their malignant potential. For this reason the initial evaluation should always include a history and physical examination focusing on features suggestive of malignancy. Serum thyrotropin (TSH) and thyroid ultrasonography (US) are pivotal in the evaluation of thyroid nodules, as they provide important information regarding thyroid nodule functionality and the presence of features suspicious for malignancy, respectively.

A thyroid nodule is a lump in the thyroid gland. The thyroid gland is located at the base of the neck and is solid or filled with fluid. It is single nodule or a cluster of nodules. A thyroid nodule is a lump in your thyroid gland. It can be solid or filled with fluid. You can have a single nodule or a cluster of nodules. Thyroid nodules are common structures and rarely cancerous. Thyroid nodules are most common in women than in men. With the age advances the chance of getting thyroid also increases. Very often, nodules produce no symptoms. It could be identified by routine physical exam or imaging tests that are done for another reason. High-impact journals are those considered to be highly influential in their respective fields. The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field. It is first devised by Eugene Garfield, the founder of the Institute for Scientific Information. The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years.