The thyroid gland produces two hormones, tri-iodothyronine (T3) and thyroxin (T4). T3 is crafted from T4 and is the extra energetic hormone. Thyroid hormones have an effect on a massive variety of metabolic pathways which include protein, carbohydrate and lipid metabolism. Thyroid hormones have an effect on metabolism, mind improvement, respiration, coronary coronary heart and concerned machine capabilities, body temperature, muscle power, pores and skin dryness, menstrual cycles, weight, and ldl cholesterol degree. Hypothyroidism is a disease that takes vicinity whilst the thyroid gland does not make sufficient thyroid hormone to fulfill the body’s wishes. Thyroid hormone production is regulated with the aid of the use of thyroid-stimulating hormone (TSH), that is made with the aid of the pituitary gland in the thoughts. When thyroid hormone ranges within the blood are low, the pituitary releases greater TSH. When thyroid hormone levels are immoderate, the pituitary responds via dropping TSH manufacturing. Hypothyroidism isn't always uncommon endocrinal disorder in popular population, especially in women and its occurrence increase with age. It influences zero.Five-2.Four% of the general population [1]. The hormone T3 plays a vital role in lipid metabolism with the aid of regulating genes worried in lipogenesis and lipolysis [2]. Thyroid hormones moreover maintain the preliminary degree of phospholipids in mobile membranes and fatty acids composition of the lipids [3]. In hyperthyroidism normally serum diploma of overall, LDL and HDL cholesterol decreases [4]. Hypercholesterolemia is determined in hypothyroidism due to the increment of low density lipoprotein cholesterol levels. High density lipoprotein cholesterol levels normally stay regular or extended