Venous thromboembolism (VTE) is a disease that includes both deep vein thrombosis (DVT) and pulmonary embolism (PE). Venous thromboembolism is of the common disorder in cardiovascular illness after acute coronary syndrome and stroke. Venous thromboembolism results from a combination of hereditary and acquired risk factors. VTE can be treated by anticoagulant therapy. Journal of Vascular Surgery: Venous and Lymphatic Disorders, Paediatric Blood and Cancer, Biology of Blood and Marrow Transplantation, Blood Cancer Journal, Blood Coagulation and Fibrinolysis, Blood Research. A 1988 article in Chest questioned the possibility that patients with Multiple Sclerosis (MS) could develop Venous Thromboembolism (VTE). Debilitation, reduced physical activity and hypo mobility are present in several neurological diseases, and already at the time a correlation had been described between Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE) and sequel of stroke and quadriplegia, but not for desalinating diseases. Doctors working with and treating these patients reported episodic events of thromboembolism, at times even fatal, which took place either at home or during periods of hospitalization, but until that point there had been no evidence that could confirm or disprove these claims. Mechanical prophylaxis with anti-embolism stockings could perhaps find a role also due to the reduced risks of complications associated with them if properly used, but targeted studies on an adequate population for the proper period of time still must be conducted.